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•     Notify shipper and the consignee.
               •     Proceed with further handling of the package only if authorized and trained. Use
                     appropriate personal protective equipment (e.g. disposable gloves)
               •     Follow established spill clean up procedures if required.

               Spill clean-up procedures

               Clean-up  or  disposal  should  only  be  carried  out  by  a  competent  person.  DO  NOT
               CLEAN-UP OR DISPOSE OF INFECTIOUS SUBSTANCES UNLESS TRAINED  OR
               UNDER SUPERVISION OF A COMPETENT PERSON.

               •     Keep unauthorised personnel away.

               •     Do not touch or walk through spilled material.

               •     Do not touch damaged containers or spilled material unless wearing appropriate
                     personal protective equipment and clothing.

               •     Be particularly careful to avoid contact with broken glass or sharp objects that may
                     cause cuts or abrasions that could significantly increase the risk of exposure.

               •     Cover the spill with a cloth or paper towels to contain it.

               •     Pour  an  appropriate  disinfectant  over  the  cloth  or  paper  towels  and  the
                     immediately surrounding area (5% bleach solutions are generally appropriate, but
                     for spills on aircraft, quaternary ammonium disinfectants should be used).

               •     Apply the disinfectant concentrically beginning at the outer margin of the spill area,
                     working towards the centre.

               •     After  about  30  min,  clear  away  the  materials.  If  there  is  broken  glass  or  other
                     sharps  are  involved,  use  a  dustpan  or  a  piece  of  stiff  cardboard  to  collect  the
                     materials and deposit them into a puncture-resistant container for disposal.

               •     Clean and disinfect the area of the spillage.

               •     Dispose  of  contaminated  materials  into  a  leak-proof,  puncture-resistant  waste
                     disposal container.

               •     Obtain identity of substance involved and report the incident and decontamination
                     to the appropriate authorities.

               •     Detailed information on disinfectants and their recommended use can be found in
                     Laboratory biosafety manual, 3rd ed., Geneva, World Health Organization, 2004.




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